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Asparaginase Search

Experimentally Studied Proteins

Fam ? Class - Clan - Family Alt ? Alternative historical name / classification AN ? UniProt accession number Name ? UniProt entry name, only given here for Swiss-Prot entries EC Organism Cell-Loc AAs Structure PDB Km i for Asn [mM] Vmax i for Asn [μmol/min/mg] Kcat i for Asn [s-1]
1-1-1 - i Sequence available in publication. No similar sequences could be found in databases. As presented, lacks the critical conserved Motif 1. 3.5.1.1 Cladosporium sp. - 370 - - 100 - -
1-1-1 - A0A4D6C6W0 3.5.1.1 Cobetia amphilecti - 316 - - 2.05 11641 -
1-1-1 - C5E3N2 3.5.1.1 Lachancea thermotolerans - 375 - - 11.67 - 312.45
1-1-1 ScAII i Identical sequences: P0CZ17, P0CX77, P0CX78, P0CX79 P0CZ17 ASP21_YEAST 3.5.1.1 Saccharomyces cerevisiae Secreted 362 - - 0.27 42 -
1-1-1 ScAI P38986 ASPG1_YEAST 3.5.1.1 Saccharomyces cerevisiae Cytoplasm 381 - - 0.075 i K0.5, allosteric enzyme - -
1-1-3 - P10172 ASPQ_ACIGL 3.5.1.38 Acinetobacter glutaminasificans Periplasm 331 Homo tetramer 1AGX - - -
1-1-3 - Q5E4M4 3.5.1.1 Aliivibrio fischeri - 353 - - 1.2275 - -
1-1-3 - UPI0002D9BB57 3.5.1.1 Bacillus altitudinis - 382 - - 0.0147 - -
1-1-3 - A0A0P7GBY8 3.5.1.1 Bacillus australimaris - 382 - - 0.0456 i Sequence may not be exact match - 74.6 i Sequence may not be exact match
1-1-3 - A0A2P8QZG9 3.5.1.1 Campylobacter blaseri - 347 - - 1.91 - 13.94
1-1-3 - Q0PC96 3.5.1.1 Campylobacter jejuni - 331 Homo tetramer 3NXK - - -
1-1-3 ErA, type II P06608 ASPG_DICCH 3.5.1.1 Dickeya chrysanthemi - 348 Homo tetramer 5F52 PDBs 0.058 i Sequence may be not be exact match - 565 i Sequence may be not be exact match. Kcat may not correspond to Km.
1-1-3 EcAII P00805 ASPG2_ECOLI 3.5.1.1 Escherichia coli Periplasm 348 Homo tetramer 3ECA PDBs 0.015 - 24
1-1-3 - A0A4Q0YCX3 3.5.1.1 Halarcobacter ebronensis - 349 - - 4.27 - 16.55
1-1-3 HpA, type II Q9ZLB9 ASPG_HELPJ 3.5.1.1 Helicobacter pylori i (strain J99 / ATCC 700824) (Campylobacter pylori J99) Cytoplasm 332 Homo tetramer 2WLT PDBs 0.29 i S0.5, Sequence may be not be exact match 31.22 i Sequence may be not be exact match 19.26 i Sequence may be not be exact match
1-1-3 - UPI0010229EFA 3.5.1.1 Iodobacter sp. - 355 - - 1.2 - 82
1-1-3 - I3DG54 3.5.1.1 Pasteurella bettyae - 349 - - 3.98 - 69.12
1-1-3 - Q7WWK9 3.5.1.1 Pectobacterium atrosepticum i (Erwinia carotovora subsp. atroseptica) - 349 Homo tetramer 2HLN
90%
0.098 732 1600
1-1-3 - P10182 ASPQ_PSES7 3.5.1.38 Pseudomonas sp. Periplasm 337 Homo tetramer 3PGA PDBs - - -
1-1-3 - i Exact sequence available in publication 3.5.1.38 Pseudomonas sp. i Himalayan Pseudomonas sp. PCH44 - 366 - - 0.56 - 18.06
1-1-3 - A0A3R9P3J0 3.5.1.1 Salibacterium salarium i Bacillus salarius - 359 - - 5.59 - 8.87
1-1-3 - A0A0H2WSV5 3.5.1.1 Salmonella paratyphi - 348 - - 28 - 39.6
1-1-3 - A0A240C149 3.5.1.1 Serratia ficaria - 349 - - 1.42 - -
1-1-3 - A0A1D8KVW6 3.5.1.1 Serratia marcescens i From soil metagenomic libraries generated from forest soil. Possibly Serratia marcescens (estimation). - 348 - - 2.0 - 15.5
1-1-3 - A0A2D3WDS0 3.5.1.1 Sulfurospirillum cavolei - 348 - - 0.63 - 10.14
1-1-3 - D1B4K0 3.5.1.1 Sulfurospirillum deleyianum - 348 - - 1.80 - 20.16
1-1-3 WsA, type II P50286 ASPG_WOLSU 3.5.1.1 Wolinella succinogenes Cytoplasm 330 Homo tetramer 1WSA PDBs 0.0217 - 97.8
1-1-3 - D3VBI4 3.5.1.1 Xenorhabdus nematophila - 347 - - 4.27 - 6.43
1-1-3 - Q66CJ2 3.5.1.1 Yersinia pseudotuberculosis - 345 - - 0.017 - -
1-2-5 - A0A3Q8UES2 3.5.1.1 Bacillus cereus - 325 Homo dimer i Determined by gel filtration chromatography - 9.38 - 63.6
1-2-5 BlA, type I P30363 ASPG_BACLI 3.5.1.1 Bacillus licheniformis Cytoplasm 322 - - - - -
1-2-5 i Very similar sequence to ASPG_BACLI, but not identical A0A6I7U6Y2 3.5.1.1 Bacillus licheniformis - 322 Homo dimer 7CB4 PDBs 2.96 - -
1-2-5 i Very similar sequence to ASPG_BACLI, but not identical A0A3G1GZN5 3.5.1.1 Bacillus licheniformis - 322 - - 0.0106 - 23.96
1-2-5 - Q5KXR8 3.5.1.1 Geobacillus kaustophilus - 323 - - 0.487 243.9 -
1-2-5 - A0A7U9P5Z0 3.5.1.1 Geobacillus thermopakistaniensis - 323 i "Biochemical characterization revealed that ASNaseGt existed in an oligomeric form in solution which can be converted to the most active tetrameric form by the addition of thiol reducers." - 0.35 2735 1595
1-2-5 - F0TGT0 3.5.1.1 Lactobacillus acidophilus - 331 - - 6.23 - 0.51
1-2-5 - A0AAD1ETD3 3.5.1.1 Lactobacillus casei - 324 - - 0.0123 i Sequence may not be exact match - -
1-2-5 - F9URL2 3.5.1.1 Lactobacillus plantarum - 324 - - 7.85 - 2.33
1-2-5 - Q38YS9 3.5.1.1 Latilactobacillus sakei - 324 Homo dimer i Determined by gel filtration - 7.64 - 4.09
1-2-5 - I6ZQC6 3.5.1.1 Melioribacter roseus - 326 - - 2.7 163 96
1-2-5 i brenda-enzymes.org, archived id J9H7D1 A0A9X4QZ02 3.5.1.1 Staphylococcus sp. - 324 Homo dimer i Size-exclusion chromatography determined - 2.2 - 4.65
1-2-5 - A0A062WR39 3.5.1.1 Streptococcus pneumoniae - 320 Monomer i Context unknown, paper to be published 9D91 i Paper to be published - - -
1-2-5 - Q5M2S9 3.5.1.1 Streptococcus thermophilus - 322 - - 2.34 - 101
1-2-6 - A0A1X1VDM8 3.5.1.1 Mycobacterium gordonae - 312 - - 6.025 - 194.8
1-2-6 - A0QX50 3.5.1.1 Mycobacterium smegmatis - 320 - - 1.403 - 708.1
1-2-6 - P9WPX5 ASPG_MYCTU 3.5.1.1 Mycobacterium tuberculosis i (strain ATCC 25618 / H37Rv), identical to P9WPX4 Secreted 315 Dimer - 0.38 8.3 19.57 74.08 797.7 1587.7 80.7 869.4 1732.5
1-4-10 - Q2RMX1 3.5.1.1 Rhodospirillum rubrum - 172 Homo tetramer i Specific tetrameric structure, as this family lacks the C-terminal stabilizing domain present in the other Class 1 families 8UOO PDBs 2.9
3.6 0.280 i Later results indicate a millimolar Km
- 57.1 58.2
1-4-11 - R4L284 ! Uncertain if sequence and kinetics data match. As presented, the protein lacks the critical conserved Motif 1. 3.5.1.1 Bacillus licheniformis - 272 - - 0.671 ! As presented, the protein lacks the critical conserved Motif 1 - 36.8 ! As presented, the protein lacks the critical conserved Motif 1
1-4-11 - A0A6G7ABJ6 3.5.1.1 Bacillus sonorensis - 329 - - 2.004 - -
1-4-11 - P26900 ASPG1_BACSU 3.5.1.1 Bacillus subtilis Cytoplasm 329 - - 1.579 i Sequence may not be exact match - -
1-4-11 - A0A291B5A4 3.5.1.1 Bacillus tequilensis - 329 - - 0.070 - -
1-4-11 - A5VMR3 3.5.1.1 Lactobacillus reuteri - 329 - - 0.3332 i Sequence may not be exact match - -
1-4-11 - A0A0R2I8I9 3.5.1.1 Limosilactobacillus secaliphilus - 333 - - 4.78 - 887
1-4-11 - Q8TZE8 ASPG_PYRFU 3.5.1.1 Pyrococcus furiosus - 326 Homo dimer / tetramer i Temperature dependent 5CBP PDBs 12 - 870
1-4-11 PhA O57797 3.5.1.1 Pyrococcus horikoshii - 328 Homo dimer 1WLS PDBs - - -
1-4-11 - F8AHM4 3.5.1.1 Pyrococcus yayanosii - 328 - - 6.5 - -
1-4-11 - C5A6T2 3.5.1.1 Thermococcus gammatolerans - 328 - - 5.3 - -
1-4-11 - Q5JIW4 ASPG_THEKO 3.5.1.1 Thermococcus kodakarensis - 328 Homo dimer 5OT0 2.6
5.5
1121 3300 694
1-4-11 - C6A532 3.5.1.1 Thermococcus sibiricus - 331 - - 4.7 640 400
1-4-11 - UPI00029ABCE1 3.5.1.1 Thermococcus zilligii - 330 - - 6.08 - 3267
1-4-12 - O26802 GATD_METTH 6.3.5.- Methanothermobacter thermautotrophicus - 435 Hetero tetramer i Has additional domain. 2D6F - - -
1-4-12 - Q9V0T9 GATD_PYRAB 6.3.5.- Pyrococcus abyssi - 438 Hetero tetramer i Has additional domain. 1ZQ1 - - -
1-5-14 CpAI H0W0T5 3.5.1.1 Cavia porcellus - 565 Homo tetramer i Additional ankrytin repeats. 4R8L PDBs 0.057 - 38.6
1-5-14 hAI Q86U10 LPP60_HUMAN 3.1.1.5 3.5.1.1 3.1.1.47 Homo sapiens - 573 Monomer i At assay conditions, substrate-inducing effect on the oligomeric state - 11.5 i S0.5, alloseric enzyme - 6.7
1-5-15 RmAI W0G253 3.5.1.1 Rhizomucor miehei - 682 Homo dimer i Determined by gel filtration. Has additional ankyrin repeats. - 0.133 i brenda-enzymes.org 3380.0 676
1-5-16 EcAI
i Identical sequences: P0A963, P0A962
P0A962 ASPG1_ECOLI 3.5.1.1 Escherichia coli i (strain K12) Cytoplasm 338 Homo tetramer i dimer of two intimate dimers 2HIM PDBs 1.2 i S0.5, allosteric enzyme
3.5
- -
1-5-16 - A0A221KKE2 3.5.1.1 Halomonas elongata - 355 - - 5.6 - 1960
1-5-16 - X0NLX5 3.5.1.1 Photobacterium leiognathi i Fish gut microbiome. Organism not certain. - 337 - - 3.008 i Sequence may not be exact match - -
1-5-16 i As presented, lacks the critical conserved Motif 1 A0A7D7L7P6 3.5.1.1 Pseudomonas aeruginosa - 306 - - 10.904 - -
1-5-16 - A0A2D5S0K3 3.5.1.1 Rheinheimera sp - 341 - - 0.98 - 16.17
1-5-16 VcA, type I Q9KQK3 3.5.1.1 Vibrio cholerae Cytoplasm 337 Homo tetramer 2OCD i Paper to be published 1.1 i Sequence may not be exact match - 4424 i Sequence may not be exact match
1-5-16 - A0A191W2U6 3.5.1.1 Vibrio sp. - 337 - - 4.517 - 2.88
1-5-16 YpAI A0A3N4B0Q2 3.5.1.1 Yersinia pestis Cytoplasm 338 Homo dimer / tetramer 7R69 PDBs 6.0 i K0.5 - 42.0
2-1-2 - D0V0N4 3.5.1.26 Asobara tabida Venom 362 - - 4.051 - -
2-1-2 - P20933 ASPG_HUMAN 3.5.1.26 Homo sapiens Lysosome 346 Hetero tetramer / homo dimer 1APY PDBs 0.656 i Sequence may not be exact match - -
2-1-2 - A0A141NXG8 3.5.1.26 Leptopilina heterotoma Venom 367 - - 1.188 - -
2-1-2 - O02467 ASPG_SPOFR 3.5.1.26 Spodoptera frugiperda Lysosome 320 - - 3.0 - -
2-1-5 - A0A1V3U2Z4 3.5.1.26 Elizabethkingia meningoseptica - 331 Hetero tetramer / homo dimer 6DEY - - -
2-1-5 - Q47898 ASPG_ELIMR 3.5.1.26 Elizabethkingia miricola Periplasm 340 Hetero tetramer / homo dimer 1AYY PDBs - - -
2-2-6 - Q8YQB1 ASGX_NOSS1 3.4.19.5 Nostoc sp. - 318 - - 2.0 2.2 -
2-2-6 - P74383 ASGX_SYNY3 3.4.19.5 Synechocystis sp. - 329 - - 0.66 1.6 -
2-3-9 - Q9H6P5 TASP1_HUMAN 3.4.25.- Homo sapiens i Overexpressed in primary human cancers. 420 Hetero tetramer / homo dimer / hexamer i Concentration dependent. 6VIN PDBs - - -
2-4-10 - A0A0N7IWY2 3.5.1.1 Aquabacterium sp. 306 - - 33.7 - 0.0087
2-4-10 - Q6L1Z2 3.5.1.1 Picrophilus torridus - 297 - - 11.69 - 0.056
2-4-10 - A3MUS8 ASPGP_PYRCJ 3.5.1.1 Pyrobaculum calidifontis - 299 Dimer i Determined from gel filtration - 4.5 355 374.0
2-4-10 - Q9V262 ASPGP_PYRAB 3.5.1.1 Pyrococcus abyssi - 305 - - 2.051 - -
2-4-10 - Q5JHT1 ASPGP_THEKO 3.5.1.1 Thermococcus kodakarensis - 306 Dimer i Determined from gel filtration - 3.1 833 -
2-4-12 CpAIII H0VQC8 3.4.19.5 3.5.1.1 Cavia porcellus 332 Hetero tetramer / homo dimer 4O47 2.24 - 3.95
2-4-12 - Q7L266 ASGL1_HUMAN 3.4.19.5 3.5.1.1 Homo sapiens Cytoplasm 308 Hetero tetramer / homo dimer 4ZM9 PDBs 3.4 - 6.9
2-4-12 - Q8VI04 ASGL1_RAT 3.4.19.5 3.5.1.1 Rattus norvegicus Cytoplasm 333 - - 2.4 - -
2-5-14 - P50287 ASPGA_ARATH 3.4.19.5 Arabidopsis thaliana - 315 - - > 4 - -
2-5-14 EcAIII P37595 IAAA_ECOLI 3.4.19.5 Escherichia coli - 321 Hetero tetramer / homo dimer 1T3M PDBs 90% 3.9 - 0.28
2-5-14 LlAIII Q9ZSD6 ASPG_LUPLU 3.4.19.5 Lupinus luteus - 325 Hetero tetramer / homo dimer 2GEZ PDBs 4.8 - 0.32
2-5-14 PvAIII V7CU13 3.4.19.5 Phaseolus vulgaris - 326 Hetero tetramer / homo dimer 4PU6 PDBs - - -
2-5-14 - UPI002B2CA93D 3.4.19.5 Solanum lycopersicum - 329 - - 0.66 - -
2-5-17 - X7EBZ8 3.4.19.5 Roseivivax halodurans - 310 Hetero tetramer / homo dimer 8DQM PDBs - - -
3-1-1 - A0A0C5GVW3 3.5.1.1 Paenibacillus barengoltzii - 336 Monomer i Determined by gel filtration. - 3.6 162.2 -
3-1-1 - A0A068N0Z8 3.5.1.1 Synechocystis sp. - 317 - - 29 25.7 -
3-2-2 - W0KM71 3.5.1.1 Nocardiopsis alba Extracellular 320 - - 0.127 5.5 -
3-2-2 - Q54237 3.5.1.1 Streptomyces griseus Extracellular (putative) 328 - - - - -
3-3-3 ReAV Q2K0Z2 3.5.1.1 Rhizobium etli - 367 Homo dimer 7OS6 PDBs 4.2 - 438
3-4-4 ReAIV Q2KB35 3.5.1.1 Rhizobium etli - 335 Homo dimer 8CLZ PDBs 1.34 - 411

Swiss-Prot Sequences

Fam ? Class - Clan - Family Alt ? Alternative historical name / classification AN ? UniProt accession number Name ? UniProt entry name, only given here for Swiss-Prot entries EC Organism Cell-Loc AAs Structure PDB Km i for Asn [mM] Vmax i for Asn [μmol/min/mg] Kcat i for Asn [s-1]
1-1-1 ScAII i Identical sequences: P0CZ17, P0CX77, P0CX78, P0CX79 P0CZ17 ASP21_YEAST 3.5.1.1 Saccharomyces cerevisiae Secreted 362 - - 0.27 42 -
1-1-1 ScAII i Identical sequences: P0CZ17, P0CX77, P0CX78, P0CX79 P0CX77 ASP22_YEAST 3.5.1.1 Saccharomyces cerevisiae Secreted 362 - - 0.27 42 -
1-1-1 ScAII i Identical sequences: P0CZ17, P0CX77, P0CX78, P0CX79 P0CX78 ASP23_YEAST 3.5.1.1 Saccharomyces cerevisiae Secreted 362 - - 0.27 42 -
1-1-1 ScAII i Identical sequences: P0CZ17, P0CX77, P0CX78, P0CX79 P0CX79 ASP24_YEAST 3.5.1.1 Saccharomyces cerevisiae Secreted 362 - - 0.27 42 -
1-1-1 - P87015 ASPG1_SCHPO 3.5.1.1 Schizosaccharomyces pombe Secreted, cell wall 360 - - - - -
1-1-1 ScAI P38986 ASPG1_YEAST 3.5.1.1 Saccharomyces cerevisiae Cytoplasm 381 - - 0.075 i K0.5, allosteric enzyme - -
1-1-1 - Q9UTS7 ASPG2_SCHPO 3.5.1.1 Schizosaccharomyces pombe Secreted, cell wall 356 - - - - -
1-1-1 - Q8NKC0 ASPG3_SCHPO 3.5.1.1 Schizosaccharomyces pombe Secreted, cell wall 360 - - - - -
1-1-1 - Q8TFF8 ASPG4_SCHPO 3.5.1.1 Schizosaccharomyces pombe Secreted, cell wall 356 - - - - -
1-1-3 - O34482 ASPG2_BACSU 3.5.1.1 Bacillus subtilis - 375 - - 0.43 - -
1-1-3 EcAII P00805 ASPG2_ECOLI 3.5.1.1 Escherichia coli Periplasm 348 Homo tetramer 3ECA PDBs 0.015 - 24
1-1-3 - P43843 ASPG2_HAEIN 3.5.1.1 Haemophilus influenzae Periplasm 349 - - - - -
1-1-3 ErA, type II P06608 ASPG_DICCH 3.5.1.1 Dickeya chrysanthemi - 348 Homo tetramer 5F52 PDBs 0.058 i Sequence may be not be exact match. - 565 i Sequence may be not be exact match. Kcat may not correspond to Km.
1-1-3 HpA, type II Q9ZLB9 ASPG_HELPJ 3.5.1.1 Helicobacter pylori i (strain J99 / ATCC 700824) (Campylobacter pylori J99) Cytoplasm 332 Homo tetramer 2WLT PDBs 0.29 i S0.5, Sequence may be not be exact match 31.22 i Sequence may be not be exact match 19.26 i Sequence may be not be exact match
1-1-3 HpA, type II O25424 ASPG_HELPY 3.5.1.1 Helicobacter pylori i (strain ATCC 700392 / 26695) (Campylobacter pylori) Cytoplasm 330 - - - - -
1-1-3 WsA, type II P50286 ASPG_WOLSU 3.5.1.1 Wolinella succinogenes Cytoplasm 330 Homo tetramer 1WSA PDBs 0.0217 - 97.8
1-1-3 - P10172 ASPQ_ACIGL 3.5.1.38 Acinetobacter glutaminasificans Periplasm 331 Homo tetramer 1AGX - - -
1-1-3 - Q9I407 ASPQ_PSEAE 3.5.1.38 Pseudomonas aeruginosa Periplasm 362 - - - - -
1-1-3 - O68897 ASPQ_PSEFA 3.5.1.38 Pseudomonas fluorescens Periplasm 362 - - - - -
1-1-3 - Q88K39 ASPQ_PSEPK 3.5.1.38 Pseudomonas putida Periplasm 362 - - - - -
1-1-3 - P10182 ASPQ_PSES7 3.5.1.38 Pseudomonas sp. Periplasm 337 Homo tetramer 3PGA PDBs - - -
1-2-5 BlA, type I P30363 ASPG_BACLI 3.5.1.1 Bacillus licheniformis Cytoplasm 322 - - - - -
1-2-6 - Q9RRX9 ASPG_DEIRA 3.5.1.1 Deinococcus radiodurans Cytoplasm 322 - - - - -
1-2-6 - P63628 ASPG_MYCBO 3.5.1.1 Mycobacterium bovis Secreted 315 - - - - -
1-2-6 - Q9X7E6 ASPG_MYCLE 3.5.1.1 Mycobacterium leprae Secreted 310 - - - - -
1-2-6 - P9WPX4 ASPG_MYCTO 3.5.1.1 Mycobacterium tuberculosis i (strain CDC 1551 / Oshkosh), identical to P9WPX5 Secreted 315 - - - - -
1-2-6 - P9WPX5 ASPG_MYCTU 3.5.1.1 Mycobacterium tuberculosis i (strain ATCC 25618 / H37Rv), identical to P9WPX4 Secreted 315 Dimer - 0.38 8.3 19.57 74.08 797.7 1587.7 80.7 869.4 1732.5
1-4-11 - P26900 ASPG1_BACSU 3.5.1.1 Bacillus subtilis Cytoplasm 329 - - 1.579 i Sequence may not be exact match - -
1-4-11 - Q8TZE8 ASPG_PYRFU 3.5.1.1 Pyrococcus furiosus - 326 Homo dimer / tetramer i Temperature dependent 5CBP PDBs 12 - 870
1-4-11 - Q5JIW4 ASPG_THEKO 3.5.1.1 Thermococcus kodakarensis - 328 Homo dimer 5OT0 2.6
5.5
1121 3300 694
1-4-12 - Q9Y9T8 GATD_AERPE 6.3.5.- Aeropyrum pernix - 427 - - - - -
1-4-12 - O29380 GATD_ARCFU 6.3.5.- Archaeoglobus fulgidus - 418 - - - - -
1-4-12 - B0R6H4 GATD_HALS3 6.3.5.- Halobacterium salinarum - 427 - - - - -
1-4-12 - Q9HP20 GATD_HALSA 6.3.5.- Halobacterium salinarum - 427 - - - - -
1-4-12 - Q18GL3 GATD_HALWD 6.3.5.- Haloquadratum walsbyi - 442 - - - - -
1-4-12 - Q8TR66 GATD_METAC 6.3.5.- Methanosarcina acetivorans - 424 - - - - -
1-4-12 - Q46GJ6 GATD_METBF 6.3.5.- Methanosarcina barkeri - 424 - - - - -
1-4-12 - Q12X65 GATD_METBU 6.3.5.- Methanococcoides burtonii - 415 - - - - -
1-4-12 - Q60331 GATD_METJA 6.3.5.- Methanocaldococcus jannaschii - 417 - - - - -
1-4-12 - Q8TV84 GATD_METKA 6.3.5.- Methanopyrus kandleri - 458 - - - - -
1-4-12 - A4FWR5 GATD_METM5 6.3.5.- Methanococcus maripaludis - 418 - - - - -
1-4-12 - A9AA46 GATD_METM6 6.3.5.- Methanococcus maripaludis - 418 - - - - -
1-4-12 - A6VGK5 GATD_METM7 6.3.5.- Methanococcus maripaludis - 418 - - - - -
1-4-12 - Q8PUM7 GATD_METMA 6.3.5.- Methanosarcina mazei - 425 - - - - -
1-4-12 - P61400 GATD_METMP 6.3.5.- Methanococcus maripaludis - 418 - - - - -
1-4-12 - A5UK11 GATD_METS3 6.3.5.- Methanobrevibacter smithii - 436 - - - - -
1-4-12 - A4YHH3 GATD_METS5 6.3.5.- Metallosphaera sedula - 439 - - - - -
1-4-12 - Q2NEH1 GATD_METST 6.3.5.- Methanosphaera stadtmanae - 438 - - - - -
1-4-12 - O26802 GATD_METTH 6.3.5.- Methanothermobacter thermautotrophicus - 435 Hetero tetramer i Has additional domain. 2D6F - - -
1-4-12 - A6UPR4 GATD_METVS 6.3.5.- Methanococcus vannielii - 426 - - - - -
1-4-12 - P61401 GATD_NANEQ 6.3.5.- Nanoarchaeum equitans - 392 - - - - -
1-4-12 - Q9V0T9 GATD_PYRAB 6.3.5.- Pyrococcus abyssi - 438 Hetero tetramer i Has additional domain. 1ZQ1 - - -
1-4-12 - Q8ZY04 GATD_PYRAE 6.3.5.- Pyrobaculum aerophilum - 417 - - - - -
1-4-12 - Q8U0X0 GATD_PYRFU 6.3.5.- Pyrococcus furiosus - 438 - - - - -
1-4-12 - O59132 GATD_PYRHO 6.3.5.- Pyrococcus horikoshii - 438 - - - - -
1-4-12 - Q97ZH5 GATD_SACS2 6.3.5.- Saccharolobus solfataricus - 444 - - - - -
1-4-12 - Q4J955 GATD_SULAC 6.3.5.- Sulfolobus acidocaldarius - 446 - - - - -
1-4-12 - C3N5E7 GATD_SULIA 6.3.5.- Sulfolobus islandicus - 445 - - - - -
1-4-12 - C4KH13 GATD_SULIK 6.3.5.- Sulfolobus islandicus - 445 - - - - -
1-4-12 - C3MPS1 GATD_SULIL 6.3.5.- Sulfolobus islandicus - 445 - - - - -
1-4-12 - C3MYR5 GATD_SULIM 6.3.5.- Sulfolobus islandicus - 445 - - - - -
1-4-12 - C3NHQ2 GATD_SULIN 6.3.5.- Sulfolobus islandicus - 445 - - - - -
1-4-12 - C3NE01 GATD_SULIY 6.3.5.- Sulfolobus islandicus - 445 - - - - -
1-4-12 - Q971W5 GATD_SULTO 6.3.5.- Sulfurisphaera tokodaii - 448 - - - - -
1-4-12 - Q9HJJ5 GATD_THEAC 6.3.5.- Thermoplasma acidophilum - 409 - - - - -
1-4-12 - Q5JI77 GATD_THEKO 6.3.5.- Thermococcus kodakarensis - 440 - - - - -
1-4-12 - A1RX40 GATD_THEPD 6.3.5.- Thermofilum pendens - 451 - - - - -
1-4-12 - Q979L8 GATD_THEVO 6.3.5.- Thermoplasma volcanium - 406 - - - - -
1-5-14 - Q9U518 ASPG_DIRIM 3.5.1.1 Dirofilaria immitis - 590 - - - - -
1-5-14 hAI Q86U10 LPP60_HUMAN 3.1.1.5 3.5.1.1 3.1.1.47 Homo sapiens - 573 Monomer i At assay conditions, substrate-inducing effect on the oligomeric state. Has additional ankyrin repeats. - 11.5 i S0.5, alloseric enzyme - 6.7
1-5-14 - A0JNU3 LPP60_MOUSE 3.1.1.5 3.5.1.1 3.1.1.47 Mus musculus - 564 - - - - -
1-5-14 - O88202 LPP60_RAT 3.1.1.5 3.5.1.1 3.1.1.47 Rattus norvegicus - 564 - - - - -
1-5-16 EcAI i Identical sequences: P0A963, P0A962 P0A963 ASPG1_ECO57 3.5.1.1 Escherichia coli i (O157:H7) Cytoplasm 338 - - - - -
1-5-16 EcAI i Identical sequences: P0A963, P0A962 P0A962 ASPG1_ECOLI 3.5.1.1 Escherichia coli i (strain K12) Cytoplasm 338 Homo tetramer i dimer of two intimate dimers 2HIM PDBs 1.2 i S0.5, allosteric enzyme
3.5
- -
2-1-2 - Q56W64 ASPG3_ARATH 3.4.19.5 Arabidopsis thaliana - 359 - - - - -
2-1-2 - Q21697 ASPG_CAEEL 3.5.1.26 Caenorhabditis elegans Lysosome 363 - - - - -
2-1-2 - B3MJ16 ASPG2_DROAN 3.5.1.26 Drosophila ananassae - 378 - - - - -
2-1-2 - B3N6Y7 ASPG1_DROER 3.5.1.26 Drosophila erecta - 396 - - - - -
2-1-2 - B3NN96 ASPG2_DROER 3.5.1.26 Drosophila erecta - 399 - - - - -
2-1-2 - B4JVW6 ASPG1_DROGR 3.5.1.26 Drosophila grimshawi - 393 - - - - -
2-1-2 - Q8MR45 ASPG1_DROME 3.5.1.26 Drosophila melanogaster - 393 - - - - -
2-1-2 - Q9W2C3 ASPG2_DROME 3.5.1.26 Drosophila melanogaster - 397 - - - - -
2-1-2 - B4GGF2 ASPG1_DROPE 3.5.1.26 Drosophila persimilis - 388 - - - - -
2-1-2 - B4GHE3 ASPG2_DROPE 3.5.1.26 Drosophila persimilis - 457 - - - - -
2-1-2 - Q28Y14 ASPG1_DROPS 3.5.1.26 Drosophila pseudoobscura - 388 - - - - -
2-1-2 - Q28XQ5 ASPG2_DROPS 3.5.1.26 Drosophila pseudoobscura - 457 - - - - -
2-1-2 - B4HT15 ASPG1_DROSE 3.5.1.26 Drosophila sechellia - 393 - - - - -
2-1-2 - B4I7X1 ASPG2_DROSE 3.5.1.26 Drosophila sechellia - 397 - - - - -
2-1-2 - B4QHB1 ASPG1_DROSI 3.5.1.26 Drosophila simulans - 393 - - - - -
2-1-2 - B4QGM0 ASPG2_DROSI 3.5.1.26 Drosophila simulans - 397 - - - - -
2-1-2 - B4NWI1 ASPG1_DROYA 3.5.1.26 Drosophila yakuba - 396 - - - - -
2-1-2 - B4P8E0 ASPG2_DROYA 3.5.1.26 Drosophila yakuba - 399 - - - - -
2-1-2 - P20933 ASPG_HUMAN 3.5.1.26 Homo sapiens Lysosome 346 Hetero tetramer / homo dimer 1APY PDBs 0.656 i Sequence may not be exact match - -
2-1-2 - Q4R6C4 ASPG_MACFA 3.5.1.26 Macaca fascicularis Lysosome 346 - - - - -
2-1-2 - Q64191 ASPG_MOUSE 3.5.1.26 Mus musculus Lysosome 346 - - - - -
2-1-2 - P30919 ASPG_RAT 3.5.1.26 Rattus norvegicus Lysosome 345 - - - - -
2-1-2 - O02467 ASPG_SPOFR 3.5.1.26 Spodoptera frugiperda Lysosome 320 - - 3.0 - -
2-1-5 - Q47898 ASPG_ELIMR 3.5.1.26 Elizabethkingia miricola Periplasm 340 Hetero tetramer / homo dimer 1AYY PDBs - - -
2-2-6 - Q8YQB1 ASGX_NOSS1 3.4.19.5 Nostoc sp. - 318 - - 2.0 2.2 -
2-2-6 - P74383 ASGX_SYNY3 3.4.19.5 Synechocystis sp. - 329 - - 0.66 1.6 -
2-3-7 - Q9P6N7 TASP1_SCHPO 3.4.25.- Schizosaccharomyces pombe Cytoplasm 345 - - - - -
2-3-8 - O65268 TASP1_ARATH 3.4.25.- Arabidopsis thaliana - 408 - - - - -
2-3-9 Taspase1 Q9H6P5 TASP1_HUMAN 3.4.25.- Homo sapiens i Overexpressed in primary human cancers. 420 Hetero tetramer / homo dimer / hexamer i Concentration dependent. 6VIN PDBs - - -
2-3-9 - Q8R1G1 TASP1_MOUSE 3.4.25.- Mus musculus - 420 - - - - -
2-4-10 - A3MUS8 ASPGP_PYRCJ 3.5.1.1 Pyrobaculum calidifontis - 299 Dimer i Determined from gel filtration - 4.5 355 374.0
2-4-10 - Q9V262 ASPGP_PYRAB 3.5.1.1 Pyrococcus abyssi - 305 - - 2.051 - -
2-4-10 - Q8U4E6 ASPGP_PYRFU 3.5.1.1 Pyrococcus furiosus - 306 - - - - -
2-4-10 - O57971 ASPGP_PYRHO 3.5.1.1 Pyrococcus horikoshii - 305 - - - - -
2-4-10 - Q5JHT1 ASPGP_THEKO 3.5.1.1 Thermococcus kodakarensis - 306 Dimer i Determined from gel filtration - 3.1 833 -
2-4-12 - Q32LE5 ASGL1_BOVIN 3.4.19.5 3.5.1.1 Bos taurus Cytoplasm 308 - - - - -
2-4-12 - Q5BKW9 ASGL1_DANRE 3.4.19.5 3.5.1.1 Danio rerio Cytoplasm 310 - - - - -
2-4-12 - Q9VXT7 ASGL1_DROME 3.4.19.5 3.5.1.1 Drosophila melanogaster - 332 - - - - -
2-4-12 - Q29I93 ASGL1_DROPS 3.4.19.5 3.5.1.1 Drosophila pseudoobscura - 325 - - - - -
2-4-12 - Q7L266 ASGL1_HUMAN 3.4.19.5 3.5.1.1 Homo sapiens Cytoplasm 308 Hetero tetramer / homo dimer 4ZM9 PDBs 3.4 - 6.9
2-4-12 - Q4R7U8 ASGL1_MACFA 3.4.19.5 3.5.1.1 Macaca fascicularis Cytoplasm 308 - - - - -
2-4-12 - Q8C0M9 ASGL1_MOUSE 3.4.19.5 3.5.1.1 Mus musculus Cytoplasm 326 - - - - -
2-4-12 - Q8VI04 ASGL1_RAT 3.4.19.5 3.5.1.1 Rattus norvegicus Cytoplasm 333 - - 2.4 - -
2-4-12 - Q6GM78 ASGL1_XENLA 3.4.19.5 3.5.1.1 Xenopus laevis Cytoplasm 309 - - - - -
2-5-14 - P50287 ASPGA_ARATH 3.4.19.5 Arabidopsis thaliana - 315 - - > 4 - -
2-5-14 - Q8GXG1 ASPGB_ARATH 3.4.19.5 Arabidopsis thaliana - 325 - - - - -
2-5-14 - Q54WW4 ASGX_DICDI 3.4.19.5 3.5.1.1 Dictyostelium discoideum - 346 - - - - -
2-5-14 EcAIII P37595 IAAA_ECOLI 3.4.19.5 Escherichia coli - 321 Hetero tetramer / homo dimer 1T3M PDBs 90% 3.9 - 0.28
2-5-14 - P50288 ASPG_LUPAL 3.4.19.5 Lupinus albus - 325 - - - - -
2-5-14 - P30364 ASPG_LUPAN 3.4.19.5 Lupinus angustifolius - 325 - - - - -
2-5-14 - P30362 ASPG_LUPAR 3.4.19.5 Lupinus arboreus - 306 - - - - -
2-5-14 LlAIII Q9ZSD6 ASPG_LUPLU 3.4.19.5 Lupinus luteus - 325 Hetero tetramer / homo dimer 2GEZ PDBs 4.8 - 0.32
2-5-14 - Q7CQV5 IAAA_SALTY 3.4.19.5 Salmonella typhimurium - 313 - - - - -
The Asparaginase Database | Release 2025-01 | Contact:
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