Asparaginase Database Statistics

2026-08

Release (first after early access)

126,085

Total Unique Sequences

101

Experimentally Studied Proteins

Asparaginase Families

Sequence Distribution by Class

Sequence and Experimentally Studied Protein Distribution by Family

Class 1 Sequences

Class 2 Sequences

Class 3 Sequences

Studied Proteins (right axis)

Insights

Class 1 dominates with 51% of all sequences (64,284) and 72 studied proteins
Class 2 comprises 34% of sequences (43,103) and 23 studied proteins
Class 3 represents 15% of sequences (18,698) and 6 studied proteins
101 proteins have been experimentally studied across 22 families
Family 1-1-3 has both the most sequences (11,814) and studied proteins (24) as well as both asparaginases in pharmaceutical use
18 families likely remain unstudied experimentally, representing potential research opportunities

Publication

If you use The Asparaginase Database or the classification in your research, please cite:

Max Štětina, Aleš Křenek, Guglielmo Tedeschi, Filip Krása, Vojtěch Spiwok, Eva Benešová, The Asparaginase Database: a comprehensive resource and classification of l‑asparaginases, Database, Volume 2026, 2026, baag045, https://doi.org/10.1093/database/baag045.

The Asparaginase Database Statistics

Sequence Distribution by Class

Sequence and Experimentally Studied Protein Distribution by Family

Sequence Distribution by Clan

Insights

Publication